Comedian Kathy Griffin has faced a backlash after tweeting about injecting Donald Trump with air ― a potentially fatal procedure that could cause an air embolism and block a blood vessel.

“Syringe with nothing but air inside it would do the trick,” she wrote in response to the US president’s pondering during a White House diabetes event on the price of insulin and whether he should take the drug.

“FUCK TRUMP,” the comedian added.

Kathy later responded to a tweet from the conservative Washington Examiner news website, which said she was advocating “for someone to stab” Trump with a syringe full of air.

“I SURE DID, FUCKER,” she replied.

The comic, who in March was hospitalised with a stomach infection amid fears she’d contracted COVID-19, faced backlash in 2017 after she posed for photographs with a fake severed head that looked like the president.

Trump called her out for the stunt, labelling her “sick”.

Kathy initially apologised, saying she went “way too far” and “was wrong.” She also was investigated by the Secret Service. 

Since then, she has retracted that apologyon multiple occasions, calling the outrage “BS” and overblown.